Where Biology, Chemistry and Physics come together

Lab Members


We want to know how cells function



A collection of our works


The latest news from the lab

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PhD in molecular cell biology and systems biology – open position September 30th, 2016

We are currently looking for one to two new PhDs for projects related to protein homeostasis and protein quality control. The projects involve work in the area of molecular cell biology and quantitative biology and we require that candidates are not […]

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New light sheet microscope for cells in a Petri dish September 13th, 2016

Light-sheet fluorescence microscopy (LSFM), also termed single plane illumination microscopy (SPIM), enables live cell fluorescence imaging with optical sectioning capabilities superior to confocal microscopy and without any out-of-focus exposure of the specimen. However, the need of two objective lenses, one […]

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Methods paper on the maltose promoter submitted to BioRxiv .. June 28th, 2016

sometimes another promoter that can be regulated like the GAL1 promoter comes in handy … here Update – the paper is now accepted in YEAST

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antisenseRNA revisited … June 28th, 2016

fist paper on a systematic functional analysis of antisense RNAs in yeast  … read here the open access pdf … and a commentary here …

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ImageJFX – a new user interface for ImageJ June 24th, 2016

With the ImageJ-FX Project we aim to create a new user interface for the software ImageJ in order to ease scientific image analysis. While keeping the core components of ImageJ and full compatibility with the current plugins, ImageJFX brings scientists closer to their goal […]

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PostDoc in Optics/Physics wanted! April 22nd, 2016

PostDoc with a background in physics/engineering and a strong interest In microscopy, optical engineering and BioImaging (Feb. 2016) Job description: Our laboratory works at the interface of physics, informatics, cell- and molecular biology, we develop new methods and microscopy instrumentation and […]

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New tools for yeast library construction March 11th, 2016

are you interested in systemic yeast research and you would like to have a new yeast library with a different feature, such as your favorite fluorescent protein, then please feel free to use the SWAp-Tag strategy go here!

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Skiretreat ahead …. from 28th to 3rd we are out of the lab …. February 26th, 2016

for science, Pizza and skiing ….

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A trial in BioRxiv September 11th, 2015

We submitted a technical manuscript for publication and simultaneously uploaded it to BioRxiv … with excellent feedback! Several people contacted us in order to obtain reagents or to discuss data…. Update (Nov’15) : We actually were contacted by people who […]

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How good is your fluorescence microscope working? August 10th, 2015

If you have no clue whether your microscope is working according to its ‘diffraction limit’ (=providing the resolution it is supposed to according of the specification of its optical part), you can now find out very easy by using a new […]

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How to duplicate a yeast gene …. August 10th, 2015

Do you want to increase the gene dosage from one copy to two copies without the hassle of cloning the gene followed by chromosomal integration, then read our small PLoS One paper, and be surprised how easy this is….PCR Duplication: A One-Step […]

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New fluorescent protein – better FCCS April 21st, 2015

our evolved long-stokes shift fluorescent protein mKeima8.5 – based on mKeima – has made it into a paper … thanks to a great collaboration with Jagesh Shah and his group and the folks at Montana State University…and hopefully soon into […]

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How to make a promoter-reporter fusion without hassle.. August 10th, 2015

Do you want to use a particular promoter to drive your reporter gene, but you are too lazy to clone the promoter into your reporter plasmid, then read how you can save some time and hassle ……..PCR Duplication: A One-Step […]

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P1070911 with Patrick

2. Position: Team from the lab with friends successful in the ‘Henkel’ Lauf May 12th, 2015

Martin, Patrick and Florian together with Katrin and Bogdan made a sensational 2nd place in the annual Henkel run – congratulations!

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Cells … June 29th, 2015

Cells are the smallest functional units of the most complex 3D objects that currently exist  …. .. and we need to understand how they function! My lab hopes to contribute to this goal by several ways. First, we develop methods to study the spatio-temporal […]

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Never touch a running system …. July 29th, 2015

but make sure you have a complete backup of the hard disc of your system installation. This lesson we had to learn the hard way, because our Nikon-TiE/FCCS System stopped working after Microsoft decided that it is time to update the system with […]

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Our new 3D printer arrived – the excitement is clearly visible April 1st, 2015

we recently decided that a 3D printer could solve several issues with custom made fabrication of microscopy parts, prototyping of metal pieces etc., …. now we bought such a device. Let’s see how useful it will become.

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EMBO Course

EMBO Course Single Molecule and Single Cell Fluorescence Å/nm/μm/mm-scopy is running …. March 14th, 2015

  Lots of cool microscopy  ….. link      

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